In our clinic, we see many ladies who current with suicidal ideation rising or worsening through the premenstrual part of the menstrual cycle. Though earlier research have reported an affiliation between Premenstrual Dysphoric Dysfunction (PMDD) and suicidal ideation, most of those research haven’t confirmed the prognosis utilizing potential rankings and DSM diagnostic standards. A latest examine from Wikman and colleagues assesses the prevalence of suicidal ideation in ladies with PMDD confirmed utilizing extra stringent standards..
On this examine, the contributors had been 110 ladies recruited to take part in a randomized placebo-controlled medical trial for the therapy of PMDD between January 15, 2017 and October 19, 2019. The prognosis of PMDD was confirmed utilizing potential every day rankings in keeping with DSM-5 standards. Present suicidal ideation was measured utilizing the MADRS-S administered through the late luteal part of the menstrual cycle.
Suicidal ideation was reported through the late luteal part by almost 40% of the ladies with confirmed PMDD (n = 43, 39.1%). Present suicidal ideation was extra frequent in ladies reporting earlier psychological therapy for PMDD (OR 5.63, 95% CI 1.07-29.49). As well as, greater depressive signs through the late luteal part had been related to suicidal ideation (OR 1.17, 95% CI 1.10-1.25). In distinction, greater rankings of self-rated well being had been related to decrease odds ratios for present suicidal ideation (OR 0.98, 95% CI 0.96-0.99).
On this inhabitants in search of therapy for PMDD, suicidal ideation is quite common, affecting about 40% of the ladies. This examine is distinct from prior research inspecting the affiliation between PMDD and suicidal ideation; within the present examine, the prognosis of PMDD was confirmed prospectively in response to DSM diagnostic standards and suicidal ideation was measured concurrently. Whereas the examine doesn’t assess suicidal ideation in a group pattern of girls with PMDD, the findings of this examine counsel that suicidal ideation is frequent amongst ladies in search of therapy for PMDD.
Ruta Nonacs, MD PhD
Wikman A, Sacher J, Bixo M, Hirschberg AL, Kopp Kallner H, Epperson CN, Comasco E, Sundström Poromaa I. Prevalence and correlates of present suicidal ideation in ladies with premenstrual dysphoric dysfunction. BMC Womens Well being. 2022 Feb 11;22(1):35.
