This submit accommodates two questions across the subject of He Shou Wu, estrogen and phytoestrogens. Right here’s the primary one:
“How can He-Sho-wu each modulate estrogen and assist males? I do know a bit about He-Sho-wu as I’ve been researching it for a number of months, I do know it doesn’t really comprise estrogen. I’m thinking about your product however I’m attempting to determine if it is going to work for my causes for buying. I must know the way the herb can each modulate estrogen and assist males with sexual well being? Wouldn’t modulation of estrogen be counterproductive for a male to take it for sexual well being? It looks like that may lower testosterone?”
Modulation means altering, as in it might go up or down.
And estrogen is definitely vital for males, together with for sexual well being! The quantity issues. Sure, many guys are estrogen dominant, however some even have too low. This text, Estrogen for Males, accommodates extra on the topic.
The fascinating factor about estrogen for males is that too excessive or too low estrogen can each result in low libido and diminished sexual operate. Most individuals don’t acknowledge that truth.
There are various different advantages to estrogen like neuroprotection as nicely.
Like “all phytoestrogens are dangerous” the concept that “males must keep away from estrogen just like the plague” is incorrect.
However is that this even He Shou Wu’s important methodology of motion? A assessment of the literature dug up a number of issues.
This research checked out He Shou Wu (Polygonum multiflora) and hypoglycemia. It recognized 38 metabolic pathways…solely considered one of which was the estrogen signaling pathway. (Prolactin was a distinct hormonal one.)
One other research checked out 5 herbs selling estrogen biosynthesis in a tumor cell line. He Shou Wu didn’t accomplish that in statistically important manner.
(Apparently this research did discover that Sexy Goat Weed, particularly it’s lively constituent icariin, did promote estrogen, in addition to enhancing aromatase, the enzyme that converts testosterone to estrogen. I discover this fairly fascinating as a result of Sexy Goat Weed is a widely known sexual tonic significantly for males, which once more exhibits the myths across the space to be false. Icariin has estrogenic motion…but is a compound within the class of PDE5-inhibitors, the identical as Viagra!)
One other research checked out estrogenic and antiestrogenic potential of many crops. He Shou Wu had weak estrogenic results. (Apparently, Cinnamon had the strongest antiestrogenic motion right here, although nonetheless fairly weak.)
This research checked out the same group of herbs, particularly cytotoxicity of tumor cell traces as a result of estrogenic motion of the herbs. Right here He Shou Wu once more confirmed some motion right here.
And lastly, one other survey of 32 Chinese language herbs to have a look at efficacy in menopausal signs. This “was assessed utilizing a recombinant yeast system with each a human estrogen receptor expression plasmid and a reporter plasmid.” In my estimation, what meaning is that it seemingly doesn’t have a lot carryover to your well being. But right here once more, He Shou Wu was proven to have weak estrogenic motion.
I’ll use that final research for instance to only how “weak” the estrogenic motion is. On this and the opposite research, the primary estrogen, estradiol is used because the management with a worth of 1. He Shou Wu’s estrogenic motion had a relative power of two.87 x 10(-4) or 0.000214. Weak certainly!
That’s the extent of what I might discover in a fast scientific literature search on the topic.
I need to reiterate that this isn’t the primary motion of He Shou Wu. Its important methods of supporting well being are in methods exterior of the endocrine system.
Let’s transfer onto the second query:
“From what I noticed on the web site, he shou wou is ready in a kind of black soybean stew, and other people keep away from soy as a result of it has a excessive stage of phytoestrogens and I believe it could sluggish thyroid operate, do you suppose the ready he shou wou might need these similar points when taken?”
That is in alignment with the current article on Are Phytoestrogens Harmful or Wholesome?
Now, right here is the unanswered query. Is the weak estrogenic motion already described from the He Shou Wu roots themselves, or is that this coming from the truth that He Shou Wu is historically ready by being cooked in black soy bean soup?
Uncooked or unprepared He Shou Wu is usually not beneficial, as it may be a robust laxative. Moreover, this preparation helps to lower the degrees of anthraquinones like emodin whereas rising others like stilbenes which might be current within the uncooked roots. In Chinese language medication ready is sort of at all times used, and in circumstances the place uncooked is used it’s thought of an entirely totally different herb.
So do He Shou Wu roots comprise their very own phyto-estrogens?
I couldn’t discover any proof of this. Not one of the compounds within He Shou Wu that I checked out, together with TSG, stilbenes, polydatin, resveratrol, emodin, physion, rhaponticin, and plenty of others, (massive listing discovered right here) are phytoestrogens.
Not considered one of them.
This leads me to consider, although I’m open to new proof, that the preparation course of lends some from the soy isoflavones to He Shou Wu. That’s the place the weak estrogenic motion comes from.
That’s my guess. It may very well be proved out by on the lookout for soy isoflavones like genistein in a completed extract. Perhaps we’ll try this with ours in some unspecified time in the future.
In any case, it is a tiny quantity. You’d truthfully get vastly extra phytoestrogens from consuming a handful of any nuts or seeds in comparison with a teaspoon of the extract powder. Sure, all nuts and seeds comprise phytoestrogens. Beer has them. Apples have them. Espresso has them. They’re far more frequent than you suppose.
Due to this fact, taking He Shou Wu is a far cry from consuming a Tofurky.
I’d say the identical factor for the thyroid or goitrogen impact of soy. Unfavorable results to the thyroid are usually seen with heavy soy diets (soy milk, tofu, pretend meat merchandise, and many others.) or different goitrogens. The quantity you’ll get from He Shou Wu is probably going subsequent to nothing. In case you have main issues along with your thyroid then perhaps this price avoiding, in any other case the vast majority of individuals might be high quality.
I’ve been taking He Shou Wu virtually day-after-day for the previous a few years. Clearly, I’m not afraid of those supposedly damaging results. And I don’t suppose any man ought to be both. That being mentioned, you should experiment and discover what works for you. I like He Shou Wu. I’m going to maintain taking it. You get to make your personal decisions.
- The phytoestrogens in He Shou Wu are a tiny quantity and weak in motion.
- Phytoestrogens can have useful results, and each women and men want estrogen. They’re additionally present in much more meals than you suppose.
- The estrogenic pathway just isn’t the primary mechanism of He Shou Wu. Most of its results are coming from non-hormonal pathways.
In case you have another questions or feedback on the subject, be sure you ask under.
Listed here are a pair different He Shou Wu deep dive articles you might be thinking about: